Mechanism of Action of Mometasone Mometasone is a topical medium potency glucocorticoid. The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits Phospholipase A2 and thus decreases the production of Prostaglandins, leukotrienes (LT), and platelet activating factor, Scientific Name: Momeatason furoate 0.1% Drag Period: Producing Company: SpimacoĪrama sonuçlarını eşleştirin: دواء Metaz 0.1% Ointment About Mometasone A glucocorticoid steroid, Anti psoriatic,anti asthma ,anti inflammatory. It stimulates the enzymes needed to decrease the inflammatory response.
It exerts highly selective glucocorticoid action. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex.
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